The incident began after police saw a grey BMW X5, being driven on the Teeraw Road.
Upon seeing the police patrol the car was driven off at speed towards Armagh city along the Ballycrummy Road and onto the Killylea Road.
At times the car drove on the wrong side of the road, and dangerously overtook other vehicles, until it crashed into another car.
The men in the BMW were arrested and herbal cannabis and cannabis vapes were found.
The 21-year-old was arrested on suspicion of a number of offences including dangerous driving, possession of class B drugs, possession of class B drugs with intent to supply and possession of criminal property.
The 22-year-old was arrested on suspicion of possession of class B drugs and possession of class B drugs with intent to supply and has since been released on police bail to allow for further enquiries to be conducted.
